BaBi RSV 

BaBi RSV Protect is a Network wide data linkage study. It uses routinely collected health data to understand who receives the RSV vaccine during pregnancy, when vaccination occurs, and how well maternal vaccination reduces infant hospital admissions with RSV in the first year of life. A key focus is on babies at higher risk, including those born prematurely and those living in more disadvantaged communities.

BaBi RSV Immune is an in depth immunological study running in selected BaBi sites. It examines how the RSV vaccine given during pregnancy leads to antibodies being passed from mother to baby, how long vaccine derived protection lasts after birth, and how vaccination timing and prematurity affect infant immune protection.

The problem

RSV is the leading cause of infant hospital admission in the UK. Babies born prematurely and those from more disadvantaged backgrounds are more likely to become seriously unwell. Although vaccination during pregnancy offers strong protection, important real world questions remain about uptake, optimal timing, and protection in high risk groups.

The response

Born in Bradford and the Born and Bred in (BaBi) Network bring together diverse communities and securely linked health records, creating a unique opportunity to answer these questions using real world evidence.

The findings

These studies will provide evidence to improve RSV vaccination programmes, reduce avoidable hospital admissions, and address health inequalities. If you would like to find out more or get involved, please speak to your local BaBi research team.

Team Contact 

Jonathan Broad

Jonathan.broad@ukhsa.gov.uk